The standard for functional safety in road vehicles (ISO 26262) requires a "safety culture" as part of safety management. A rather narrow definition of safety culture provided by this standard primarily refers to processes and human resources. However, a safety culture requires much more than processes and human resources. Unfortunately, it is not easy to grasp what the term safety culture exactly means. And it is even more challenging to develop the desired final state: a safety-oriented mindset throughout the organization. Employees and managers have to shift their mindset towards this safety culture. In addition to appropriate processes, guidelines, and a clear safety strategy, the mindset and, consequently, the actions of people are essential for sustainable change. Together, employees of organizations need to change these components: the strategy, processes, and the mindset of the organization’s members, to develop a safety culture for the long term. Only with these changes, organizations can efficiently achieve product safety and compliance with the respective safety standards. Companies are aware of the required strategy and process changes, but the necessary cultural change is rather hard to grasp and is a long-term process. This presentation gives insights into the concept of a safety culture and shows which significance it has for product safety. It also introduces approaches for how to achieve a cultural change.